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Notification report


Full notification file


General information

Notification Number
B/NL/19/004

Member State to which the notification was sent
Netherlands

Date of acknowledgement from the Member State Competent Authority
21/02/2019

Title of the Project
MC2 TCR T cells -T cells retrovirally engineered to express a MAGE-C2 specific T cell receptor

Proposed period of release:
01/01/2019 to 01/01/2030

Name of the Institute(s) or Company(ies)
Erasmus MC, Erasmus MC
s-Gravendijkwal 230
Afdeling Urologie
Rotterdam 3015 CE
The Netherlands;


3. Is the same GMO release planned elsewhere in the Community?
Yes:
Austria; Belgium; Germany; Denmark; Spain; Finland; France; United Kingdom; Greece; Ireland; Italy; Luxembourg; Portugal; Sweden; Iceland; Norway;

Has the same GMO been notified elsewhere by the same notifier?
No

GMO characterization

GMO is a:
RNA Virus

Identity of the GMO:
Autologous patient peripheral blood T cells, that are ex vivo transduced with a replication-deficient viral vector (pMP71, isolated from a murine Moloney Murine Leukemia Virus) to express a αβ TCR (MAGE-C2 specific TCR16) of human origin.

Information relating to the recipient or parental organisms from wich the GMO is derived
Common NameGenusSpeciesSubspeciesStrainPathovar
HumanHomoSapiens---

European Commission administrative information

Consent given by the Member State Competent Authority:
Not known