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Notification report


General information

Notification Number
B/DE/02/146

Member State to which the notification was sent
Germany

Date of acknowledgement from the Member State Competent Authority
08/11/2002

Title of the Project
Evaluation of transgenic potato plants as bioreactors for the production of non-plant spider silk proteins under field conditions

Proposed period of release:
01/01/2003 to 31/12/2004

Name of the Institute(s) or Company(ies)
Institute of Plant Genetics and Crop Plant Research, Gatersleben;


3. Is the same GMPt release planned elsewhere in the Community?
No

Has the same GMPt been notified elsewhere by the same notifier?
No

Genetically modified plant

Complete name of the recipient or parental plant(s)
Common NameFamily NameGenusSpeciesSubspeciesCultivar/breeding line
potatosolanaceaesolanumsolanum tuberosumtuberosumSolara

2. Description of the traits and characteristics which have been introduced or modified, including marker genes and previous modifications:
The transgenic plants carry the selectable marker nptII and a gene coding for a spider silk-elastin fusion protein.

Genetic modification

3. Type of genetic modification:
Insertion;

In case of insertion of genetic material, give the source and intended function of each constituent fragment of the region to be inserted:
In addition to sequences of the vector pCB 301 transgenic plants carry the genes coding for a spider silk protein, a elastin-like peptide, the CaMV35S promoter, the legumin B4 signal peptide from Vicia faba, the cmyc-tag, the KDEL coding sequence, the CaMV-35S terminator, the nptII gene from E.coli under control of the nopalin synthase promoter from A. tumefaciens and the nos terminator.

6. Brief description of the method used for the genetic modification:
The genetic modification was brought about by Agrobacterium-mediated gene transfer.

7. If the recipient or parental plant is a forest tree species, describe ways and extent of dissemination and specific factors affecting dissemination:
not applicable

Experimental Release

1. Purpose of the release:
Evaluation of the gm potatoes as bioreactors for the production of spider silk proteins.

2. Geographical location of the site:
The field release will be at the IPK Gatersleben in Gatersleben, Saxony-Anhalt

3. Size of the site (m2):
100 m2 in 2003, 500 m2 in 2004

4. Relevant data regarding previous releases carried out with the same GM-plant, if any, specifically related to the potential environmental and human health impacts from the release:
no previous releases

Environmental Impact and Risk Management

Summary of the potential environmental impact from the release of the GMPts:
Due to the absence of sexual compatible wild species and in the light of the modification carried out, no obvious environmental risks can be seen.

Brief description of any measures taken for the management of risks:
The release site will be monitored during and after the release. Potato plants not intended to be used for experimental purposes will not be grown in the vicinity of the release site.

Summary of foreseen field trial studies focused to gain new data on environmental and human health impact from the release:
not applicable

Final report
-

European Commission administrative information

Consent given by the Member State Competent Authority:
Yes
13/06/2003 00:00:00
Remarks: