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Notification report


Full notification file


General information

Notification Number
B/NL/11/001

Member State to which the notification was sent
Netherlands

Date of acknowledgement from the Member State Competent Authority
09/08/2011

Title of the Project
Ex vivo retroviral transduction of human T lymphocytes with melanoma-specific T cell receptor genes

Proposed period of release:
01/01/2011 to 01/10/2021

Name of the Institute(s) or Company(ies)
Netherlands Cancer Institute, Nederlands Kanker Instituut;


3. Is the same GMO release planned elsewhere in the Community?
No

Has the same GMO been notified elsewhere by the same notifier?
No

GMO characterization

GMO is a:
RNA Virus

Identity of the GMO:
The GMO released into the environment are ex vivo retroviral transduced, autologous T cells that are administered intravenously to patients.
Used retrovirus for transduction: Gammaretrovirus, Moloney murine leukemia virus


Information relating to the recipient or parental organisms from wich the GMO is derived
Common NameGenusSpeciesSubspeciesStrainPathovar
MoMLVGammaretrovirusMoloney murine leukemia virusoncovirinae type Cdl587rev mutant

European Commission administrative information

Consent given by the Member State Competent Authority:
Not known